Effect of a Hop Extract Standardized in 8-Prenylnaringenin …

Atlantia is a world-class provider of human clinical studies. For over a decade we have delivered clinical results to our many clients around the world, on time and on budget. We strive to offer the highest quality science while maintaining a cost-conscious approach to maximize the value proposition for each of our clients.


Introduction
1

Materials and Methods
2

Study Design and Participants
2

Study Product
3

Bone Measurements by Dual-Energy X ray Absorptiometry
4

Biomarkers of Bone Turnover and Biochemical Analysis
4

Plasma and Urine Prenylflavonoids and Their Metabolites
4

Dietary Intake, and Physical Activity Level, and Quality of Life
5

Gut Microbiome Analysis
5

Fecal Samples Collection and DNA Extraction
5

Libraries Preparation and Shotgun Metagenomic Sequencing
6

Analysis of Overall Association and Taxonomic Profile
6

Quantification of SCFA
6

Compliance and Adverse Events
7

Power Calculation and Statistical Analysis
7

Results
8

Baseline Characteristics of the Study Population
8

Safety and Compliance to the Intervention
8

DXA Parameters
9

Biochemical Analysis
11

Antropometrics, Physical Activity, Dietary Intake and Health-Related Quality of Life
12

Gut Microbiome Modulation
12

Discussion
13

References
17

Powered by