Bifidobacterium breve Bif195 Protects Against Small-intesti…

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Supplementary Figure 3. Box-plot showing the Bray-Curtis dissimilarity of stool microbial

composition, comparing Visit 2 with later visits (V3-V7). The boxed extends from the first quartile

(Q1) to the third quartile (Q3) and the line within the box shows the median value. The lower

whisker extends to the smallest value within Q1 - 1.5 x inter-quartile range (IQR) and the upper

whisker extends to the largest value within Q3 + 1.5 x IQR. Values outside the whiskers are shown

as circles.

Supplementary Figure 4. Representative images obtained by Video Capsule Endoscopy from one

subject throughout intervention period. All images are obtained from the first tertile of the small

intestine. The pictures shows: (a) Visit 2 with normal intestinal mucosa, (b) Visit 3 with normal

intestinal mucosa, (c) Visit 4 with Ulcer highlighted by blue circle, (d) Visit 4 with villous edema,

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(e) Visit 5 with Ulcer highlighted by blue circle, (f) Visit 5 villous edema highlighted by blue circle,

(g) Visit 6 with ulcer highlighted by blue circle and (h) Visit 7 with normal intestinal mucosa.

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