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Figure Legends
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Figure 1. CONSORT flow diagram.
Figure 2. Probiotic and herbal blend improves serum SCFA levels in the asthmatic population. 328 Significant increases in serum short chain fatty acid (SCFA) levels as broken down by A) all 329 asthmatic participants, B) asthmatic non-smokers, and C) asthmatic smokers. * P <0.05, ** P <0.01, 330 *** P <0.001. 331 Figure 3. Global microbiome community composition not disrupted by probiotic 332 administration, but asthmatics have a different gut microbiome. ( A ) Alpha diversity is unaltered 333 by probiotic administration. B ) Beta diversity remains similar following probiotic administration. 334 Asthmatic patients have different alpha diversity ( C ) and beta diversity ( D ). 335 Figure 4. Abundance of probiotic Lactobacillus strains increases in stool of participants. In 336 healthy participants, the concentration [ng] of A) L. plantarum increased significantly and L. 337 acidophilus and L. rhamnosus trended upward from baseline to Week 4 after supplementation. B) % 338 densitometry of L. plantarum and L. acidophilus increased significantly and L. rhamnosus trended 339 upward from baseline to Week 4. In asthmatic participants, the concentration [ng] of C) all three 340 Lactobacillus strains increased significantly from baseline to Week 4 after supplementation. D) % 341 densitometry of L. plantarum and L. acidophilus increased significantly and L. rhamnosus trended 342 upward from baseline to Week 4. * P <0.05, ** P <0.01 343
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