Contents 2 - Introduction 3 - What are postbiotics? 4 - Prebiotics vs probiotics vs postbiotics: What is the difference? 5 - Postbiotics and their microbial producers
7 - Postbiotic product applications 9 - Clinical implications and methods 12 - Clinical trial summary 13 - Postbiotics future opportunities for the industry 14 - About Atlantia
INTRODUCTION
Recent understanding of the microbiome‘s role in health and disease prompted the development of innovative solutions that will help modulate its composition and restore its appropriate func- tion. Postbiotics, as a wide collection of non-via- ble cells, metabolites, and bioactive components of microbial origin, are examples of the prepara- tions, when applied, that might bring benefits for the human body. Although the potential of these bioactives might vary greatly, the majority of them have been attributed with potent antimicrobial, antioxidant and immunomodulatory properties, which can lead to favourable physiological, immu- nological, neuro-hormonal, regulatory and met-
abolic responses. Postbiotics, in comparison to probiotics, prebiotics or synbiotics, a combination of both, have additional benefits of extended shelf- life, better stability and no need for use of live mi- croorganisms making them appealing as nutrition- al additives and preservatives of food products, as well as treatments targeted to individuals with dysregulated immune function or small children (Żółkiewicz et al., 2020). Although the advantages of using postbiotics might be exciting, it needs to be noted that further research is needed to con- firm their effectiveness and safety to improve their function and clinical validity.
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