A randomized, double blind, parallel, placebo‐controlled st…

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WANG et al .

FIGURE 4 Fecal microbiota composition and diversity analysis of subjects. (a) PCoA represented by Bray-Curtis Dissimilarity based on both LP N1115 and placebo groups over time ( p > .05). (b) Inverse Simpson and Chao-1 diversity using repeated measures based on OTUs between two groups over time. (c) RDA shows samples separate based on gender, age and treatment. Top 1000 OTU values. (d) Pie charts showing the relative abundance of the fecal microbiota at phylum level between the two groups at week 0, 4 and 8. (e) Differences in the relative abundance of Lactobacillus spp. in LP N1115 group at week 4 and week 8 was detected as significantly different using DESEq ( p < .05)

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