Bifidobacterium breve Bif195 Protects Against Small-intesti…

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Supplementary table 2. Discontinued subjects overview.

Subject ID

Trial product taken

Aspirin taken

Baseline Lewis score

Reason for trial discontinuation

Bif195/placebo

1013

Subject became pregnant. Contraindicates continuation.

Placebo

yes

yes

0

1026

Withdrawal for personal reasons

Placebo

yes

yes

184

1029

Baseline VCE capsule did not reach caecum. Contraindicates continuation.

Bif195

No

No

-

1042

Baseline VCE capsule retained in stomach. Contraindicates continuation.

Placebo

No

No

-

1048

Withdrawal for personal reasons

Bif195

yes

yes

0

1077

Baseline VCE capsule retained in stomach. Contraindicates continuation.

Placebo

No

No

-

1083

Baseline VCE capsule did not reach caecum. Contraindicates continuation.

Placebo

No

No

-

1089

SAE due to prolonged hospitalisation (back pain). Event unrelated to intake of trial product.

Placebo

yes

yes

67.5

1108

Withdrawal for personal reasons

Bif195

yes

yes

67.5

Supplementary Figure 1: Trial design.

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