Bifidobacterium breve Bif195 Protects Against Small-intesti…

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Table 2. Trial adverse events overview.

Treatment

Bif195

Placebo

Total

N (%) E N (%) E N (%) E

Number of subjects

38

37

75

14 (37.8) 20

All adverse events

8 (21.1) 12

22 (29.3) 32

Back pain

1 ( 2.6) 1

0 (0) 0

1 (1.3) 1

Blocked sinuses

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Chest infection

1 (2.6) 1

0 (0) 0

1 (1.3) 1

Cold and flu

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Cold flu symptoms

1 (2.6) 1

0 (0) 0

1 (1.3) 1

Cold/flu symptoms including a nose bleed.

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Cough, nasal congestion

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Cramping in the stomach

1 (2.6) 1

0 (0) 0

1 (1.3) 1

MANUSCRIPT 1 (2.6) 1 0 (0) 0 1 (1.3) 1 1 (2.6) 1 2 (5.4) 2 3 (4.0) 3 0 (0) 0 1 (2.7) 1 1 (1.3) 1

Cystitis

Headache

Headache, sore throat, rhinorrhea.

Heartburn

0 (0) 0

2 (5.4) 2

2 (2.7) 2

Inflammation in kidneys due to kidney stones

1( 2.6) 1 0(0) 0

1 (1.3) 1

Lower abdominal pain

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Nasal congestion

1 (2.6) 1

0 (0) 0

1 (1.3) 1

Nausea

1 (2.6) 1

0 (0) 0

1 (1.3) 1

Nausea, vomiting, headache, fatigue

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Pain and discomfort in the stomach and gut region.

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Pain and discomfort in the stomach/gut region.

1 (2.6) 1

0 (0) 0

1 (1.3) 1

Pain/discomfort in the stomach and gut region.

0 (0) 0

1 (2.7) 1

1 (1.3) 1

Painful headache which caused vomiting, thigh and back pain.

0 (0) 0

1 (2.7) 1

1 (1.3) 1

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