Probiotics and Weight Management
Executive Summary Visceral adipose tissue accumulation is currently an important research target because of its connection to metabolic disturbances, cardiovascular disease and type 2 diabetes. This study illustrates how Atlantia designed and conducted a study to investigate the outcome of probiotics supplementation in body composition and weight management assessed through DXA scans.
The research clinic that the companyownsandoperates in Cork seemed a perfect fit to recruit overweight subjectswithinthesponsors expected timeline.
Challenges and Objectives
The rationale for the current study is toperforma follow-up randomizedcontrolled trial to continue to build the evidence for this probiotic strain in the area of weight management. The sponsors needed a trusted partner able to access to the required study population, with enough expertise to design and conduct a gold-standard trial with probiotics to achieve the following objectives: • To determine the effect of daily administration of a probiotic strain on Visceral Adipose Tissue (VAT), as well as on other secondary biomarkers and efficacy parameters. • To determine the effect of a daily administration of a probiotic strain on faecal characteristics. How Atlantia’s Solution Helped Atlantia’s world-class team of nutritionists and research nurses worked closely with the Sponsors’ researchers to design and deliver the study objectives. Ireland has one of the highest rates of obesity in Europe. The percentage of people who were classified as overweight or obese in 2015 was 60% (Irish Health Survey), and this has risen to 62% in 2017 (CSO). The research clinic that the company owns and operates in Cork seemed a perfect fit to recruit overweight subjects within the sponsors expected timeline. The company’s expertise measuring VAT by DXA was a key factor on the conduction of this project.
atlantiaclinicaltrials.com
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